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Cooperative Assessment of Late Effects for SCD Curative TherapiesRecruiting
NCT05153967N/AUpdated Jul 27, 2026
Sponsor: Vanderbilt University Medical Center
Sickle Cell Disease · Pulmonary Disease · Renal Disease · Heart Disease
United States
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney DiseaseRecruiting
NCT06830629Phase 2Updated Jul 27, 2026
Sponsor: Maze Therapeutics
Proteinuric Kidney Disease
United States, France, United Kingdom
Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)Recruiting
NCT05404139Phase 2Updated Jul 27, 2026
Sponsor: University Health Network, Toronto
Metastatic Prostate Cancer
Canada
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus ErythematosusRecruiting
NCT07260877Phase 2Updated Jul 27, 2026
Sponsor: Ventus Therapeutics U.S., Inc.
Cutaneous Lupus Erythematosus (CLE) · Systemic Lupus Erythematosus · SLE · SLE (Systemic Lupus)
United States, Bulgaria, France, Georgia, Hungary +3 more
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerRecruiting
NCT07155174Phase 2Updated Jul 27, 2026
Sponsor: AbbVie
Small Cell Lung Cancer
United States, Belgium, China, Germany, Israel +7 more
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)Recruiting
NCT07244211NAUpdated Jul 27, 2026
Sponsor: University of Southern California
Femoral Neck Fractures
United States, Canada, Spain, United Kingdom
Chemotherapy With or Without Immunotherapy for Peritoneal MesotheliomaRecruiting
NCT05001880Phase 2Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Peritoneal Malignant Mesothelioma
United States
Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.Recruiting
NCT07686835Phase 2Updated Jul 27, 2026
Sponsor: Radboud University Medical Center
Melanoma (Skin) Stage IV · Melanoma (Skin Cancer) · Melanoma Metastatic · Melanoma Advanced
Netherlands
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)Recruiting
NCT06966700Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Breast Neoplasms · Triple Negative Breast Neoplasms · HR Low-Positive/HER2-Negative Breast Neoplasms
United States, Argentina, Australia, Belgium, Brazil +34 more
A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast CancerRecruiting
NCT07205822Phase 3Updated Jul 27, 2026
Sponsor: AstraZeneca
Breast Cancer
United States, China, France, Italy, South Korea +1 more
Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical CarcinomaRecruiting
NCT06487481Phase 1Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Adrenocortical Carcinoma (ACC) · Recurrent Adrenocortical Carcinoma (ACC) · Recurrent Abdominal Adrenocortical Carcinoma (ACC) · Carcinoma, Adrenocortical
United States
The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial AneurysmsRecruiting
NCT07143019NAUpdated Jul 27, 2026
Sponsor: phenox Inc.
Hemorrhagic Stroke · Aneurysm, Intracranial · Saccular Aneurysm · Fusiform Aneurysm
United States
Observational Study of Advanced Data Analytics in Genetic ConditionsRecruiting
NCT05657405N/AUpdated Jul 27, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Genetic Conditions
United States
PyroEVs/PLIN3 Mediate Lipid Droplet-Mitochondrial Coupling in Sepsis Endothelial InjuryRecruiting
NCT07727265N/AUpdated Jul 27, 2026
Sponsor: Zhongda Hospital
Sepsis
China
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)Recruiting
NCT07513376Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
United States, Australia, Canada, Germany, Greece +8 more
An Open-Label, Two-Cohort, Pharmacokinetic Study in a Maximal Use Setting for Patients With Actinic Keratosis on the Upper Extremities or the FaceRecruiting
NCT07729579Phase 1Updated Jul 27, 2026
Sponsor: Sun Pharmaceutical Industries Limited
Actinic Keratosis (AK)
United States
Intrathecal Pump Refills at Home or at the HospitalRecruiting
NCT07727798NAUpdated Jul 27, 2026
Sponsor: Moens Maarten
Intrathecal Pump Refill
Belgium
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous TreatmentRecruiting
NCT06589804Phase 3Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Metastatic Head and Neck Squamous Cell Carcinoma · Metastatic Hypopharyngeal Squamous Cell Carcinoma · Metastatic Laryngeal Squamous Cell Carcinoma · Metastatic Oral Cavity Squamous Cell Carcinoma
United States
A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical CancerRecruiting
NCT05838521Phase 2Updated Jul 27, 2026
Sponsor: Yale University
Cervical Cancer
United States
Virtual Reality (VR) Self-Hypnosis SoftwareRecruiting
NCT06398847NAUpdated Jul 27, 2026
Sponsor: Icahn School of Medicine at Mount Sinai
Musculoskeletal Pain · Neuropathic Pain · Neuralgia
United States
Genetic Analysis of Uncommon Disease Presentations in Non-US PopulationsRecruiting
NCT06595940N/AUpdated Jul 27, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Undiagnosed Diseases · Rare Diseases
Mauritius
Genomic Services Research ProgramRecruiting
NCT02595957N/AUpdated Jul 27, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Colon Cancer · Breast Cancer
United States
Feasibility Study of the FARAFLEX Mapping and PFA SystemRecruiting
NCT06510556NAUpdated Jul 27, 2026
Sponsor: Boston Scientific Corporation
Atrial Fibrillation · Persistent Atrial Fibrillation · Paroxysmal AF
Belgium, Croatia, Czechia, Italy
Enhancing Attention in Elderly Using a Brain-Computer-InterfaceRecruiting
NCT07441122NAUpdated Jul 27, 2026
Sponsor: University of Texas at Austin
Mild Cognitive Impairment (MCI)
United States
Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Adults With Newly Diagnosed HypertensionRecruiting
NCT07728630N/AUpdated Jul 27, 2026
Sponsor: Josip Juraj Strossmayer University of Osijek
Hypertension · Endothelial Function
Croatia

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