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Friday, September 11

Intelligence landscape

Structured registry intelligence cross-referenced with ClinicalTrials.gov — signal velocity, sector activity, and entity monitoring. Breast Cancer leads active signals with 2,446 open studies.

Explore entities
503,173
Tracked entities
64,609 (13%)
Active signals
4,126
Phase III active
38,403
New signals (YTD)
101,985
Record updates (YTD)
4,267
Avg signals / mo

Daily Intelligence Brief

Today's lead story

Recurring editorial brief structured from registry signals — the flagship intelligence feed for enterprise subscribers.

ClinicalTrials.gov count · refreshed hourly

Breast Cancer leads recruiting activity on ClinicalTrials.gov

Friday, September 11, 2026 · Template brief

ClinicalTrials.gov currently lists 503,173 registered studies, with 64,609 open to enrollment. 4,126 Phase III trials are actively recruiting — the late-stage pipeline that often signals upcoming readouts and regulatory decisions.

Breast Cancer has 2,446 recruiting studies, making it one of the most active therapeutic areas in the registry today. Use Explore to filter by condition, sponsor, or intervention.

  • 503,173 trials on ClinicalTrials.gov
  • 64,609 recruiting
  • 4,126 Phase III recruiting
  • Breast Cancer: 2,446 recruiting
  • 38,403 new trials posted YTD

Signal velocity

Registration velocity

New signal postings and record updates — primary indicators of sector momentum on ClinicalTrials.gov.

ClinicalTrials.gov count · refreshed hourly

1,396

New registrations (MTD)

7,001

Registry updates (MTD)

4,267

Avg registrations / month (YTD)

2.7×

Update-to-registration ratio (YTD)

Monthly registry activity

New study registrations and record updates on ClinicalTrials.gov
New registrationsRegistry updates

Cumulative YTD registrations

Running registration and update totals for 2026
New registrationsRegistry updates

Pipeline

Pipeline status

9% of Phase III studies are open for enrollment. 0% interventional; 86% of allocatable studies are randomized.

ClinicalTrials.gov count · refreshed hourly

Overall status distribution

Registered studies by overall status on ClinicalTrials.gov

Enrollment by phase

Registered studies vs open enrollment by development phase
Registered studiesOpen enrollment

Study design distribution

Interventional, observational, and expanded access studies

Study design counts load from ClinicalTrials.gov.

Randomization model

Registered studies with randomized vs non-randomized allocation

Therapeutic areas

Indication & intervention coverage

Breast Cancer leads open enrollment with 2,446 recruiting studies. 28% of open-enrollment studies are Phase III–IV.

ClinicalTrials.gov count · refreshed hourly

Trials by indication

Registered studies vs open enrollment by therapeutic area

Trials by intervention

Open enrollment and registered studies by intervention or modality

Entities

Entity portfolio

Pfizer leads with 6,081 tracked entities, 237 active signals.

ClinicalTrials.gov count · refreshed hourly

Sponsor portfolio volume

Registered studies and open enrollment by sponsor
Registered studiesOpen enrollment

Open enrollment rate by sponsor

Share of each sponsor portfolio actively enrolling patients

Top entities

Ranked by tracked entity count

  1. 1

    Pfizer

    237 open enrollment · 4% enrollment rate

    6,081

    entities

  2. 2

    Merck

    345 open enrollment · 7% enrollment rate

    5,213

    entities

  3. 3

    Novartis

    273 open enrollment · 5% enrollment rate

    5,085

    entities

  4. 4

    GSK

    138 open enrollment · 3% enrollment rate

    4,953

    entities

  5. 5

    AstraZeneca

    375 open enrollment · 8% enrollment rate

    4,804

    entities

  6. 6

    Sanofi

    145 open enrollment · 4% enrollment rate

    3,431

    entities

  7. 7

    Roche

    175 open enrollment · 6% enrollment rate

    3,159

    entities

  8. 8

    Johnson & Johnson

    3 open enrollment · 1% enrollment rate

    267

    entities

Market movers

Notable trials

Late-stage and recently updated studies from recent registry activity.

Browse Phase III →

Study history

Active study threads

Chronological change threads for studies Trial Radar is tracking — status moves, enrollment updates, geography, and protocol edits grouped by sync.