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Tuesday, July 28

Intelligence landscape

Structured registry intelligence cross-referenced with ClinicalTrials.gov — signal velocity, sector activity, and entity monitoring. Breast Cancer leads active signals with 2,467 open studies.

Explore entities
499,531
Tracked entities
65,451 (13%)
Active signals
4,111
Phase III active
31,923
New signals (YTD)
89,071
Record updates (YTD)
4,560
Avg signals / mo

Daily Intelligence Brief

Today's lead story

Recurring editorial brief structured from registry signals — the flagship intelligence feed for enterprise subscribers.

ClinicalTrials.gov count · refreshed hourly

Breast Cancer leads recruiting activity on ClinicalTrials.gov

Tuesday, July 28, 2026 · Template brief

ClinicalTrials.gov currently lists 499,531 registered studies, with 65,451 open to enrollment. 4,111 Phase III trials are actively recruiting — the late-stage pipeline that often signals upcoming readouts and regulatory decisions.

Breast Cancer has 2,467 recruiting studies, making it one of the most active therapeutic areas in the registry today. Use Explore to filter by condition, sponsor, or intervention.

  • 499,531 trials on ClinicalTrials.gov
  • 65,451 recruiting
  • 4,111 Phase III recruiting
  • Breast Cancer: 2,467 recruiting
  • 31,923 new trials posted YTD

Signal velocity

Registration velocity

New signal postings and record updates — primary indicators of sector momentum on ClinicalTrials.gov.

ClinicalTrials.gov count · refreshed hourly

4,003

New registrations (MTD)

15,662

Registry updates (MTD)

4,560

Avg registrations / month (YTD)

2.8×

Update-to-registration ratio (YTD)

Monthly registry activity

New study registrations and record updates on ClinicalTrials.gov
New registrationsRegistry updates

Cumulative YTD registrations

Running registration and update totals for 2026
New registrationsRegistry updates

Pipeline

Pipeline status

9% of Phase III studies are open for enrollment. 0% interventional; 86% of allocatable studies are randomized.

ClinicalTrials.gov count · refreshed hourly

Overall status distribution

Registered studies by overall status on ClinicalTrials.gov

Enrollment by phase

Registered studies vs open enrollment by development phase
Registered studiesOpen enrollment

Study design distribution

Interventional, observational, and expanded access studies

Study design counts load from ClinicalTrials.gov.

Randomization model

Registered studies with randomized vs non-randomized allocation

Therapeutic areas

Indication & intervention coverage

Breast Cancer leads open enrollment with 2,467 recruiting studies. 28% of open-enrollment studies are Phase III–IV.

ClinicalTrials.gov count · refreshed hourly

Trials by indication

Registered studies vs open enrollment by therapeutic area

Trials by intervention

Open enrollment and registered studies by intervention or modality

Entities

Entity portfolio

Pfizer leads with 6,057 tracked entities, 239 active signals.

ClinicalTrials.gov count · refreshed hourly

Sponsor portfolio volume

Registered studies and open enrollment by sponsor
Registered studiesOpen enrollment

Open enrollment rate by sponsor

Share of each sponsor portfolio actively enrolling patients

Top entities

Ranked by tracked entity count

  1. 1

    Pfizer

    239 open enrollment · 4% enrollment rate

    6,057

    entities

  2. 2

    Merck

    347 open enrollment · 7% enrollment rate

    5,180

    entities

  3. 3

    Novartis

    273 open enrollment · 5% enrollment rate

    5,058

    entities

  4. 4

    GSK

    132 open enrollment · 3% enrollment rate

    4,935

    entities

  5. 5

    AstraZeneca

    374 open enrollment · 8% enrollment rate

    4,778

    entities

  6. 6

    Sanofi

    151 open enrollment · 4% enrollment rate

    3,421

    entities

  7. 7

    Roche

    185 open enrollment · 6% enrollment rate

    3,153

    entities

  8. 8

    Johnson & Johnson

    3 open enrollment · 1% enrollment rate

    271

    entities

Market movers

Notable trials

Late-stage and recently updated studies from recent registry activity.

Browse Phase III →

Study history

Active study threads

Chronological change threads for studies Trial Radar is tracking — status moves, enrollment updates, geography, and protocol edits grouped by sync.