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Results for “Parkinson disease”

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)-China ExtensionCompleted
NCT04934722Phase 3Updated Sep 2, 2026
Sponsor: Merck Sharp & Dohme LLC
Metastatic Hormone-Sensitive Prostate Cancer
China
Anodic Stimulation in Parkinson's DiseaseActive Not Recruiting
NCT07798999NAUpdated Sep 2, 2026
Sponsor: University of South Florida
Parkinson Disease (PD)
United States
To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot StudyRecruiting
NCT06339398N/AUpdated Sep 2, 2026
Sponsor: Casa di Cura San Raffaele Cassino
Parkinson Disease
Italy
Exercise & Brain Energetics in PDActive Not Recruiting
NCT04426786NAUpdated Sep 2, 2026
Sponsor: Pacific Parkinson's Research Centre
Parkinson Disease
Canada
A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSARecruiting
NCT07604116Phase 1Updated Sep 1, 2026
Sponsor: Synusight Biotech (Shanghai) Co., Ltd.
Multiple System Atrophy (MSA) · Parkinson's Disease (PD)
China
A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care TherapyRecruiting
NCT07161414Phase 1Updated Sep 1, 2026
Sponsor: AstraZeneca
Advanced Solid Tumors
United States, South Korea, Spain, United Kingdom
Imaging Biomarkers in Parkinson s DiseaseCompleted
NCT01496599N/AUpdated Sep 1, 2026
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
United States
Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson DiseaseRecruiting
NCT07227896N/AUpdated Sep 1, 2026
Sponsor: AbbVie
Parkinson's Disease
United States, Israel, Romania, United Kingdom
Biofluid Research on Age-Related or Inherited NeurodegenerationRecruiting
NCT07798700N/AUpdated Sep 1, 2026
Sponsor: University of Pennsylvania
Frontotemporal Degeneration (FTD) · ALS (Amyotrophic Lateral Sclerosis) · Primary Progressive Aphasia (PPA) · Familial Frontotemporal Lobar Degeneration (fFTLD)
United States
Agricultural Health Study Follow-upCompleted
NCT01399411N/AUpdated Sep 1, 2026
Sponsor: National Institute of Environmental Health Sciences (NIEHS)
Asthma · Parkinson's Disease
United States
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal CancersActive Not Recruiting
NCT05152147Phase 3Updated Sep 1, 2026
Sponsor: Jazz Pharmaceuticals
Gastric Neoplasms · Gastroesophageal Adenocarcinoma · Esophageal Adenocarcinoma
Argentina, Australia, Belgium, Brazil, Canada +28 more
A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Physician's Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (MK-4280A-008)Completed
NCT05508867Phase 2Updated Sep 1, 2026
Sponsor: Merck Sharp & Dohme LLC
Hodgkin Lymphoma
United States, Argentina, Australia, Belgium, Brazil +15 more
Deep Brain Stimulation Surgery for Movement DisordersRecruiting
NCT01581580NAUpdated Sep 1, 2026
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson's Disease · Essential Tremor · Dystonia
United States
Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease TremorRecruiting
NCT06993571NAUpdated Sep 1, 2026
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Parkinson's Disease (PD) · Tremor
Germany
Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's DiseaseActive Not Recruiting
NCT05894343Phase 1, Phase 2Updated Sep 1, 2026
Sponsor: MeiraGTx, LLC
Parkinson's Disease
United States
Optimizing Adaptive DBS for Parkinson's DiseaseRecruiting
NCT07798271NAUpdated Sep 1, 2026
Sponsor: University of California, Davis
PARKINSON DISEASE (Disorder)
United States
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's DiseaseRecruiting
NCT06565195Phase 1Updated Sep 1, 2026
Sponsor: Prevail Therapeutics
Parkinson's Disease
United States, Germany, Japan, Netherlands, United Kingdom
Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)Completed
NCT04305041Phase 1, Phase 2Updated Sep 1, 2026
Sponsor: Merck Sharp & Dohme LLC
Melanoma
United States, Australia, France, Israel, Italy +2 more
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)Recruiting
NCT06788912Phase 2Updated Sep 1, 2026
Sponsor: Merck Sharp & Dohme LLC
Lung Neoplasm Malignant
United States, Chile, Greece, Hungary, Italy +4 more
Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)Active Not Recruiting
NCT05377281Phase 1Updated Aug 31, 2026
Sponsor: Craig van Horne, MD, PhD
Parkinson's Disease
United States
Wearable for Assessing Tremor and Continuous Health in Parkinson's Disease and Essential TremorNot Yet Recruiting
NCT07787299N/AUpdated Aug 31, 2026
Sponsor: Heriot-Watt University
PARKINSON DISEASE (Disorder)
United Kingdom
Digital Patient Engagement in Technology-Supported NeurorehabilitationNot Yet Recruiting
NCT07794072N/AUpdated Aug 31, 2026
Sponsor: Catholic University, Italy
Stroke · Parkinson Disease (PD) · Motor Neuron Disease · Spinal Cord Injury
Italy
A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS SurgeryRecruiting
NCT06683378Phase 1Updated Aug 31, 2026
Sponsor: Craig van Horne, MD, PhD
Parkinson's Disease
United States
Deep Brain Stimulation Therapy in Movement DisordersRecruiting
NCT02119611NAUpdated Aug 31, 2026
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson's Disease
United States
Constipation and Changes in the Gut Flora in Parkinson's DiseaseCompleted
NCT05787756N/AUpdated Aug 31, 2026
Sponsor: University of Aberdeen
Parkinson Disease
United Kingdom

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