NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

Constipation and Changes in the Gut Flora in Parkinson's Disease

NCT05787756

CompletedN/A

Sponsor: University of Aberdeen

Conditions: Parkinson Disease

Countries: United Kingdom

The aim of this study is to investigate the link between gut health and Parkinson's disease

Eligibility overview

Sex: ALL

Age: 18 Years to 110 Years

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

Participants with Parkinson's disease 2. Community-dwelling patients with newly diagnosed PD who have not yet started medication for Parkinson's disease.

Control Participants

1\. Healthy (non-Parkinsonian) members of the participants household will be invited to act as controls.

Exclusion Criteria:

1. Use of oral or intravenous antibiotics in the last 8 weeks.
2. Active gastrointestinal disease, not including constipation or irritable bowel syndrome without other symptoms.
3. Current use of medications which cause/worsen constipation e.g., opioids, tramadol, gabapentin, pregabalin.
4. Potential controls will be excluded if they report prodromal symptoms of PD, such as anosmia or rapid eye movement (REM) sleep disorder or display parkinsonian signs on examination.
5. Inability to give informed consent at any stage of the study e.g., because of dementia.

Locations (1)

Aberdeen, Aberdeen City, United Kingdom