NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery

NCT07809425

RecruitingNA

Sponsor: Menoufia University

Conditions: Obese Patients

Interventions: We hypothesize that adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption., Bilateral EOIB + fentanyl 1 μg/kg loading + normal saline loading (equivalent volume) + normal saline infusion (equivalent rate).

Countries: Egypt

Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing adverse events.

Eligibility overview

Sex: ALL

Age: 18 Years to 60 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Age 18-60 years.
* BMI ≥ 35 kg/m².
* ASA physical status II or III.
* Scheduled for elective laparoscopic Roux en Y gastric bypass.
* Ability to provide written informed consent.

Exclusion Criteria:

* Refusal.
* Allergy or contraindication to lidocaine, fentanyl, ropivacaine, or any study medication.
* Chronic opioid use or dependence.
* Significant hepatic (AST/ALT\> 3× normal, cirrhosis) or renal impairment (CrCl\< 30 mL/min).
* Second or third degree AV block or significant bradyarrhythmia without pacemaker.
* Coagulopathy, anticoagulation incompatible with regional anesthesia, or infection at block site.
* Pregnancy or lactation.
* Severe psychiatric or cognitive disorder.
* Failed bilateral EOIB (absence of sensory loss in T6-T10 after 30 min) - excluded from analysis.

Locations (1)

Alexandria, Egypt