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Subclinical Renal Dysfunction in Rheumatoid Arthritis

Not Yet RecruitingN/A

Sponsor: Assiut University

Conditions: Rheumatoid Arthritis, Renal Dysfunction, Chronic Kidney Diseases

This comparative cross-sectional study aims to determine the prevalence of subclinical renal dysfunction in patients with rheumatoid arthritis and to evaluate its association with disease activity and inflammatory markers compared with age- and sex-matched healthy controls at Assiut University Hospitals.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Age 18 years or older
* For patient group: Diagnosis of rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria
* For control group: Age- and sex-matched apparently healthy individuals with no history of autoimmune disease or chronic kidney disease
* Willingness to provide written informed consent

Exclusion Criteria:

* Known chronic kidney disease
* Acute kidney injury
* Diabetes mellitus
* Uncontrolled hypertension
* Active urinary tract infection
* Pregnancy
* History of obstructive uropathy or renal stones
* Systemic lupus erythematosus or other connective tissue diseases
* Malignancy
* Patients on maintenance hemodialysis