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Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)

NCT07725926

RecruitingNA

Sponsor: University College London Hospitals

Conditions: Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal, Tic Disorders, Tic Disorder, Combined Vocal and Multiple Motor, Tourette Disease

Interventions: Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention

Countries: United Kingdom

Obsessive-Compulsive Disorder and Tic Disorders frequently co-occur, and a subgroup of patients - those with a Tourettic Subtype of OCD (TOCD) - present with concurrent obsessive-compulsive and tic symptoms. Existing psychological interventions typically target one condition or the other, but rarely both together. This study aims to test whether a combined psychological therapy integrating Exposure and Response Prevention (ERP) and Habit Reversal (HbRT) is more effective at reducing symptoms than either therapy delivered alone, in adults with TOCD.

Eligibility overview

Sex: ALL

Age: 18 Years to 65 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

1. Age 18 years or older
2. All genders
3. Confirmation of a primary diagnosis of either:

a. Tourettes Disorder / Tourette Syndrome b. Persistent Motor or Vocal Tic Disorder / Chronic Motor or Vocal Tic Disorder c. Provisional Tic Disorder / Transient Motor Tics d. Other Specified Tic Disorder e. Unspecified Tic Disorder f. Obsessive-Compulsive Disorder \[d\] Participants taking psychotropic medication are eligible provided medication type and dose remain stable throughout the intervention period \[e\] Ability to provide sustained informed consent \[f\] A minimum score of 16 on YBOCS \[g\] A minimum score of 5 on the Premonitory Urge for Tics Scale (PUTS)

Exclusion Criteria:

1. Substance misuse
2. Current diagnosis of a personality disorder
3. Schizophrenia
4. Bipolar disorder
5. Contraindications to participation in a trial (i.e., active suicidal ideations and/or requirement of an interpreter)
6. Any psychiatric or neurological condition that, in the opinion of the investigators, would interfere with participation or interpretation of study outcomes.

Locations (2)

London, London, United Kingdom
London, London, United Kingdom