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Impact of Exercise on Muscle Metabolism and Function for Persons With Parkinsons

NCT07720713

CompletedNA

Sponsor: University of Texas Southwestern Medical Center

Conditions: Parkinson

Interventions: Home Exercise Program

Countries: United States

This investigation assesses the impact of a strengthening program on muscle metabolism in the gastrocnemius muscle (GM) and is an essential step in the establishment of future clinical intervention for the GM in people with Parkinson's disease (with healthy peers as the control group). The participants will be provided with a progressive GM strengthening program while monitoring muscle metabolism and functional changes before and after intervention.

Eligibility overview

Sex: ALL

Age: 50 Years to 80 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* 50-80 years of age, males and females, individuals with and without PD
* Hoehn and Yahr stages 1- 4 (if diagnosed with PD)
* Bilateral Heal Raise - minimum of 10 repetitions

Exclusion Criteria:

* Unable to walk for \>5 minutes at a time with or without an assistive device
* Any comorbidity limiting exercise

Locations (1)

Dallas, Texas, United States