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Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow
Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow

NCT07719166

CompletedN/A

Sponsor: Pirogov Russian National Research Medical University

Conditions: COVID-19, Emergency Surgery, Abdominal Surgery, Real-World Data

Interventions: Surgical and Interventional Management of Acute Surgical Conditions

Countries: Russia

The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing different acute surgical diseases (ASD). The research is based on real-world data (RWD) from a large multidisciplinary hospital repurposed as a COVID-19 center. The study analyze the mutual impact of these two acute conditions on patient outcomes, develop prognostic models for in-hospital mortality, and evaluate changes in surgical approaches during the pandemic.

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Age 18 years or older.
* Hospitalization at the MMCC "Kommunarka".
* A confirmed diagnosis of COVID-19 (based on current clinical guidelines).
* Presence of one or more any acute surgical diseases (ASD) considered competing with COVID-19 or as a complication of COVID-19/its treatment, as per the discharge summary.
* For specific sub-studies: Patients with acute surgical diseases of the abdominal organs.
* For specific sub-studies: Patients with clinically significant spontaneous soft tissue hematomas or pneumomediastinum or other acute surgical diseases.

Exclusion Criteria:

* Patients for whom a diagnosis of COVID-19 was not established according to the discharge summary.
* Patients for whom none of the studied acute surgical diseases were established according to the discharge summary.
* Patients who underwent elective surgeries and developed COVID-19 in the postoperative period.
* Patients operated on in another hospital and transferred with suspected COVID-19 (if not confirmed).
Locations (1)
  • Moscow, Russia