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Sponsor: University of Warmia and Mazury in Olsztyn
Conditions: Obesity (BMI>30)
Interventions: MRI
Countries: Poland
The goal of this observational study is to evaluate changes in adipose tissue and skeletal muscle distribution using magnetic resonance imaging (MRI) in adults with obesity undergoing bariatric surgery. The study also aims to investigate the relationship between MRI-derived body composition parameters and metabolic outcomes following surgical treatment of obesity. The main questions it aims to answer are: How does bariatric surgery affect the distribution of visceral, subcutaneous, hepatic, perirenal adipose tissue and skeletal muscle over 12 months? Are changes in MRI-derived body composition associated with improvements in metabolic parameters after bariatric surgery? Participants will: undergo MRI examinations before bariatric surgery and at 1, 6, and 12 months after surgery; undergo routine clinical and metabolic assessments during standard postoperative follow-up; have MRI-derived body composition measurements correlated with metabolic outcomes over the 12-month follow-up period.
Sex: ALL
Age: 18 Years to —
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * Age 18 years or older * BMI \>= 30 kg/m2 * qualified to undergo bariatric surgery * Ability to provide written informed consent * Willingness to undergo magnetic resonance imaging before surgery and 3, and 12 months after surgery Exclusion Criteria: * Previous bariatric surgery * Presence of ferromagnetic implants or other contraindications to magnetic resonance imaging * Previous plastic or surgical procedures affecting the body region assessed by MRI, except cholecystectomy, appendectomy, or inguinal hernia repair * Chronic kidney disease stage 4 or higher * Pregnancy * Claustrophobia preventing MRI examination * Inability or unwillingness to provide informed consent
- Olsztyn, Warminsko-mazusrkie, Poland