NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis
Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis

NCT07646470

CompletedNA

Sponsor: Osteoflow Health Clinic

Conditions: Rheumatoid Arthritis (RA

Interventions: Trans-auricular vagus nerve stimulation

Countries: Canada

The goal of this clinical trial is to learn if chronic self-administrated non-invasive vagus nerve stimulation works to improves the disease activity in a single asplenic patient suffering from rheumatoid arthritis. It will also learn about the safety of at-home chronic non-invasive vagus nerve stimulation. The main questions it aims to answer are: Does chronic non-invasive vagus nerve stimulation improves the disease activity? Does chronic non-invasive vagus nerve stimulation decrease CRP serum level? Does chronic non-invasive vagus nerve stimulation improve HRV and the sympathy-vagal balance? Participant will: Stimulate at home the left auricular branch of the vagus nerve for 24 months with three different protocol of stimulation (parameters and duration) Visit the clinic once every 2 months for checkups and tests Will have blood work for CRP level check every 8 months

Eligibility overview

Sex: MALE

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* diagnosed RA
* splenectomy

Exclusion Criteria:

Pharmaceutical treatment as:

* disease-modifying antirheumatic drugs (DMARDs)
* Biologics
* Jak inhibitors
Locations (1)
  • Moncton, New Brunswick, Canada