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DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

RecruitingN/A

Sponsor: Alnylam Pharmaceuticals

Conditions: Transthyretin Amyloidosis With Cardiomyopathy

Countries: United States, Germany, Japan

The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care * Describe treatment patterns of adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess health-related quality of life (HRQOL) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess healthcare resource use (HCRU) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Compare the long-term effectiveness of vutrisiran versus other approved ATTR-CM treatments in routine clinical care

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Has a diagnosis of ATTR-CM
* Is initiating treatment with vutrisiran or another approved ATTR-CM therapy

Exclusion Criteria:

* Is enrolled in an interventional clinical trial

Locations (24)

Tucson, Arizona, United States
Beverly Hills, California, United States
Naples, Florida, United States
Kansas City, Kansas, United States
Boston, Massachusetts, United States
St Louis, Missouri, United States
New Brunswick, New Jersey, United States
Charlotte, North Carolina, United States
Philadelphia, Pennsylvania, United States
Memphis, Tennessee, United States
Dallas, Texas, United States
Heidelberg, Germany
Munich, Germany
Münster, Germany
Bunkyō City, Japan
Kumamoto, Japan
Kurume, Japan
Matsumoto, Japan
Sendai, Japan
Shinjuku, Japan
Suita, Japan
Tsukuba, Japan
Ube, Japan
Yufu, Japan