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The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

RecruitingN/A

Sponsor: Brigham and Women's Hospital

Conditions: Rheumatoid Arthritis (RA, Atherosclerotic Cardiovascular Disease (ASCVD)

Interventions: high sensitivity cardiac troponin

Countries: United States

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

Eligibility overview

Sex: ALL

Age: 35 Years to 79 Years

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* RA diagnosed by a rheumatologist
* Age 40- 79
* ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking

Exclusion Criteria:

* Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
* Patients with diabetes mellitus
* Pregnancy

Locations (3)

Boston, Massachusetts, United States
Boston, Massachusetts, United States
Boston, Massachusetts, United States