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Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection

NCT07275827

RecruitingPhase 3

Sponsor: Tanta University

Conditions: HELICOBACTER PYLORI INFECTIONS

Interventions: zinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin

Countries: Egypt

this Study Evaluating Safety and Effectiveness of (Proton Pump Inhibitor versus Vonoprazan) Based Triple Therapy with or without Zinc to Eradicate H. pylori Infection

Eligibility overview

Sex: ALL

Age: 19 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Age \> 18.
* Both males and females.
* Patients who are positive for H.pylori infection by non-invasive Stool Antigen Test (SAT).

Exclusion Criteria:

* Prior H. pylori treatment: Previous treatment for H. pylori infection.
* Allergies: Known allergies to study medications or components.
* Patients cannot finish treatment course.
* Pregnant and Lactating Women.
* Patients with Kidney disease and eGFR \< 30ml/min.
* Patients with Liver disease with Child-Pugh B or C.

Locations (1)

Shibīn al Kawm, Egypt