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Staging Strategies and Their Association With Prognosis and Therapy in Lung Cancer With Cystic Airspaces

RecruitingN/A

Sponsor: Central South University

Conditions: Lung Cancer Associated With Cystic Airspaces

Countries: China

The goal of this observational study is to determine the most accurate tumor size measurement method for T-staging and prognostic assessment in lung cancer with cystic airspaces (LCCA). The main questions it aims to answer are: * What is the optimal T-staging approach for accurately classifying lung cancer with cystic airspaces （LCCA) and predicting patient outcomes? * How do imaging features of cystic lesions correlate with their pathological characteristics? * What is the relationship between imaging features of cystic airspace-associated lesions and patient prognosis? * Can optimizing the T-staging method improve clinical decision-making in patients with LCCA?

Eligibility overview

Sex: ALL

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

1. Histologically confirmed non-small cell lung cancer (NSCLC), as verified by biopsy or postoperative pathological examination;
2. Patients who have undergone surgical lung resection;
3. Patients with complete preoperative chest CT imaging data;
4. Preoperative chest CT showing a well-defined gas-containing (air-filled) cystic component within the tumor.

Exclusion Criteria:

1. History of pulmonary diseases that could produce cystic lung lesions (e.g., tuberculosis, pulmonary fungal infections, bullae, emphysema, Lymphangioleiomyomatosis \[LAM\], or Birt-Hogg-Dubé \[BHD\] syndrome);
2. Systemic anti-tumor therapies, including chemotherapy, radiotherapy, or targeted therapies (such as monoclonal antibodies, small-molecule tyrosine kinase inhibitors, among others), were administered prior to enrollment;
3. Patients with concurrent other malignancies;
4. Patients with missing or poor-quality preoperative chest CT imaging data.

Locations (1)

Changsha, Hunan, China