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Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Not Yet RecruitingNA

Sponsor: VA Office of Research and Development

Conditions: Overweight/Obesity, Stress

Interventions: Exercise

Countries: United States

The purpose of this study is to learn more about how common lifestyle interventions, such as exercise, affect how our brains respond to performing thinking tasks and to viewing pictures of foods and various other objects. The investigators are also interested in how changes in hormones that might be different in men and women could affect how lifestyle interventions change these brain responses.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Veterans 18-75 years old
* BMI of 25 or greater
* Physically inactive
* Able to attend study visits in person in Aurora, CO

Exclusion Criteria:

* Currently pregnant
* History of bariatric surgery
* Current eating disorder
* Current treatment with appetite-altering medications (e.g., GLP-1 agonists)
* Contraindication to MRI (weight \> 500 lbs; claustrophobia; metal or electronic devices in the body)
* Cardiovascular disease, chronic kidney disease, pulmonary disease, or diabetes
* Unable to exercise due to cardiac, pulmonary, neurologic, or orthopedic reasons

Locations (1)

Aurora, Colorado, United States