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Avacostar - (PASS)

Active Not RecruitingN/A

Sponsor: Vifor Fresenius Medical Care Renal Pharma

Conditions: ANCA-associated Vasculitis

Countries: Germany, United Kingdom

The Avacostar PASS is a non-interventional, multi-national, prospective cohort study that will collect data from 2 cohorts of patients: those treated with avacopan for active severe AAV, and a second cohort treated with a cyclophosphamide or rituximab-based induction regimen without avacopan for active severe AAV. The overall study duration is anticipated to be up to 7 years, including a recruitment period of approximately 3 years.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Diagnosis of AAV (MPA or GPA), as determined by the Investigator according to their usual practice.
* Active, severe AAV at the time of commencing avacopan or non-avacopan SoC induction therapy, in the opinion of the Investigator.
* Age ≥18 years of either sex.
* Has provided written informed consent.
* Has commenced within the previous 6 months, or is planned to commence avacopan, cyclophosphamide or rituximab for the treatment of severe, active AAV outside of an interventional clinical study.

Exclusion Criteria:

* Concurrent participation in an interventional study, unless prospectively discussed and agreed with the Medical Monitor.

Locations (35)

Berlin, Germany
Cologne, Germany
Dresden, Germany
Essen, Germany
Freiburg im Breisgau, Germany
Göttingen, Germany
Hamburg, Germany
Hanover, Germany
Herne, Germany
Munich, Germany
Plochingen, Germany
Sendenhorst, Germany
Birmingham, United Kingdom
Bradford, United Kingdom
Bristol, United Kingdom
Cambridge, United Kingdom
Canterbury, United Kingdom
Cardiff, United Kingdom
Carshalton, United Kingdom
Coventry, United Kingdom
Exeter, United Kingdom
Glasgow, United Kingdom
Leicester, United Kingdom
London, United Kingdom
London, United Kingdom
London, United Kingdom
London, United Kingdom
London, United Kingdom
Manchester, United Kingdom
Nottingham, United Kingdom
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