NCT lookup
Pull any trial record directly from ClinicalTrials.gov.
Sponsor: Massachusetts General Hospital
Conditions: HIV Infections, Tuberculosis, Smoking Cessation
Interventions: QUIT-AD, Enhanced Treatment as Usual
Countries: South Africa
The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among individuals with HIV and/or TB in Cape Town, South Africa. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiveness/implementation testing. This program will has the potential to dramatically improve public health by increasing the smoking quit rate and facilitating favorable HIV/TB treatment outcomes among patients with HIV and/or TB in resource limited South African settings.
Sex: ALL
Age: 18 Years to —
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: 1. Aged 18 or older 2. Willing and able to provide written informed consent 3. Living with HIV, confirmed via medical record, and history of taking ART for at least three months (consecutively or non-consecutively) 4. Within 4 months of initiating or reinitiating TB treatment; positive GeneXpert test or sputum culture 5. Habitual smoker operationalized as smoking at least 4 days a week 6. Motivation (\> 5/10) to quit smoking or \> 24 hour quit past yr 7. Must be living in the catchment area for either the Town Two Clinic or the Michael Mapongwana Community Health Clinic in Khayelitsha Exclusion Criteria: 1. Current interfering untreated/unstable mental health condition (e.g., psychosis, bipolar dx) 2. Current use of non-study pharmacotherapy for smoking cessation, 3. Cognitive Behavioral Therapy for smoking cessation initiated within the past year, 4. Diagnosed with extra-pulmonary or drug resistant (MDR or XDR) TB based upon chart review
- Rondebosch, South Africa