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DiEt ChoIce to Promote Type 2 Diabetes rEmission
DiEt ChoIce to Promote Type 2 Diabetes rEmission

NCT05710900

Active Not RecruitingNA

Sponsor: University of British Columbia

Conditions: Type 2 Diabetes

Interventions: Dietary intervention

Countries: Canada

Type 2 diabetes is typically viewed as a chronic, progressive, and lifelong condition. Patients and their healthcare providers "manage" type 2 diabetes through lifestyle modifications and various types of medications designed to lower blood sugar. Exciting new research indicates that "remission" of type 2 diabetes - defined as returning blood sugar into the normal range without having to use medications - through therapeutic nutrition may be possible for many people living with the condition. We will examine the preference, adherence and clinical results of a low-calorie diet or low-carbohydrate diet in type 2 diabetes remission rates.

Eligibility overview

Sex: ALL

Age: 20 Years to 80 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Aged 20-80 years old
* Diagnosed with T2D by a physician,
* HbA1c ≥ 6.0%,
* Body Mass Index ≥27 kg/m2 and
* No contraindications or dietary restrictions to following a low-carbohydrate/low-calorie diet.

Exclusion Criteria:

* History of heart disease, heart attack, heart failure, stroke or coronary artery disease within the previous 2 years,
* any current unstable cardiovascular disorder,
* history of liver disease,
* history of kidney disease with eGFR \<30 mls/min/1.73 m2,
* history of neurological disease,
* previous bariatric surgery,
* weight loss (≥5%) within the last six months
* currently pregnant or lactating, or planning on becoming pregnant within the next 12 months,
* history of cancer within the previous 5 years,
* dietary restrictions or allergies that would inhibit adherence to the intervention diet,
* history of eating disorders,
* moderate or severe depression, anxiety or mental health condition that impacts daily life,
* currently following a low-carbohydrate or low-calorie diet, and
* unable to access the Internet (for communication with research team and RD).
Locations (1)
  • Kelowna, British Columbia, Canada