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A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's DiseaseRecruiting
NCT07298421Phase 3Updated Sep 8, 2026
Sponsor: Hoffmann-La Roche
Moderately to Severely Active Crohns Disease
United States, Australia, Brazil, Mexico, South Africa +3 more
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)Recruiting
NCT07007065Phase 3Updated Sep 8, 2026
Sponsor: AbbVie
Neovascular Age-related Macular Degeneration
United States, Austria, Belgium, Bulgaria, Canada +12 more
Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)Recruiting
NCT07509151Phase 3Updated Sep 8, 2026
Sponsor: AstraZeneca
Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV
United States, Australia, Canada, Turkey (Türkiye), United Kingdom
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung CancerRecruiting
NCT06712316Phase 2, Phase 3Updated Sep 4, 2026
Sponsor: BioNTech SE
Non-small Cell Lung Cancer
United States, Australia, Belgium, Brazil, Bulgaria +15 more
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate CancerRecruiting
NCT07751133Phase 3Updated Sep 4, 2026
Sponsor: University College, London
Prostate Cancer · mHSPC · mCRPC
United Kingdom
A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in AsthmaRecruiting
NCT07309614Phase 3Updated Sep 4, 2026
Sponsor: Université de Sherbrooke
Asthma Control
Australia, Canada, United Kingdom
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)Recruiting
NCT07157774Phase 3Updated Sep 4, 2026
Sponsor: Eli Lilly and Company
Elevated Lp(a) · Atherosclerotic Cardiovascular Disease (ASCVD)
United States, Argentina, Australia, Austria, Belgium +23 more
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)Recruiting
NCT07144280Phase 3Updated Sep 4, 2026
Sponsor: Pfizer
Non-small Cell Carcinoma · Non-Small Cell Lung Cancer Metastatic · Non-Small Cell Lung Carcinoma
United States, Argentina, Australia, Belgium, Brazil +24 more
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc DiseaseRecruiting
NCT07254806Phase 3Updated Sep 4, 2026
Sponsor: DiscGenics, Inc.
Degenerative Disc Disease
United States
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightRecruiting
NCT07533175Phase 3Updated Sep 4, 2026
Sponsor: Novo Nordisk A/S
Diabetes Mellitus · Overweight · Obesity
United States, Argentina, Brazil, Croatia, Hungary +5 more
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic LeukaemiaRecruiting
NCT01949129Phase 2, Phase 3Updated Sep 4, 2026
Sponsor: St. Anna Kinderkrebsforschung
Acute Lymphoblastic Leukaemia
Argentina, Australia, Austria, Belarus, Belgium +26 more
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic AlterationsRecruiting
NCT07291037Phase 3Updated Sep 4, 2026
Sponsor: AstraZeneca
Non-small Cell Lung Cancer (NSCLC)
United States, Australia, Austria, Belgium, Brazil +16 more
A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe EczemaRecruiting
NCT06807268Phase 3Updated Sep 4, 2026
Sponsor: Pfizer
Eczema
United States, China, Germany, Hungary, Japan +3 more
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)Recruiting
NCT07218146Phase 3Updated Sep 4, 2026
Sponsor: Zai Lab (Shanghai) Co., Ltd.
Small-cell Lung Cancer
United States, Austria, Belgium, China, Czechia +10 more
A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic AcidosisRecruiting
NCT07355062Phase 3Updated Sep 4, 2026
Sponsor: Renibus Therapeutics, Inc.
CKD · Metabolic Acidosis
United States
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)Recruiting
NCT07222332Phase 3Updated Sep 4, 2026
Sponsor: Eli Lilly and Company
Diabetes Mellitus, Type 1
United States, Australia, Belgium, Brazil, Canada +15 more
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid LeukemiaRecruiting
NCT07022678Phase 3Updated Sep 4, 2026
Sponsor: Children's Oncology Group
Acute Myeloid Leukemia · Recurrent Acute Myeloid Leukemia
United States
Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line TherapyRecruiting
NCT07479797Phase 3Updated Sep 4, 2026
Sponsor: Kite, A Gilead Company
Relapsed or Refractory Large B-cell Lymphoma
United States, Australia, Canada, United Kingdom
Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal MelanomaRecruiting
NCT07804186Phase 3Updated Sep 4, 2026
Sponsor: IDEAYA Biosciences
Uveal Melanoma
Canada
The CDK4/6 Inhibitor Dosing Knowledge (CDK) StudyRecruiting
NCT06377852Phase 3Updated Sep 4, 2026
Sponsor: American Society of Clinical Oncology
Metastatic Breast Cancer
United States
Study of d-MAPPS™ Ophthalmic Solution in Adults With Chronic Ocular Graft-Versus-Host Disease (oGVHD)Recruiting
NCT07776210Phase 3Updated Sep 4, 2026
Sponsor: Regenerative Ocular Immunobiologics LLC
oGVHD · Ocular Graft Versus Host Disease
United States
A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe EczemaRecruiting
NCT07765888Phase 3Updated Sep 4, 2026
Sponsor: Pfizer
Atopic Dermatitis
United States
Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip SurgeriesRecruiting
NCT07467356Phase 3Updated Sep 4, 2026
Sponsor: Benha University
Pain Management
Egypt
Phase 3 Study of LUM-201 in Children With Growth Hormone DeficiencyRecruiting
NCT06948214Phase 3Updated Sep 4, 2026
Sponsor: Lumos Pharma
Growth Hormone Deficiency (GHD)
United States, Argentina, Australia, Chile, India +3 more
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)Recruiting
NCT06236438Phase 2, Phase 3Updated Sep 4, 2026
Sponsor: AbbVie
Non-Small Cell Lung Cancer
United States, Australia, Belgium, Chile, France +7 more

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