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A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian CancerRecruiting
NCT07213804Phase 3Updated Jul 24, 2026
Sponsor: Eli Lilly and Company
Ovarian Neoplasms · Fallopian Tube Neoplasms · Peritoneal Neoplasms · Neoplasm Metastasis
United States, Australia, Austria, Belgium, Brazil +21 more
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)Recruiting
NCT05139017Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: Merck Sharp & Dohme LLC
DLBCL · Diffuse Large B-Cell Lymphoma
United States, Argentina, Australia, Brazil, Canada +21 more
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus ErythematosusRecruiting
NCT06617325Phase 3Updated Jul 24, 2026
Sponsor: UCB Biopharma SRL
Systemic Lupus Erythematosus
United States, Argentina, Belgium, Canada, Chile +17 more
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung CancerRecruiting
NCT04181060Phase 3Updated Jul 24, 2026
Sponsor: National Cancer Institute (NCI)
Advanced Lung Non-Squamous Non-Small Cell Carcinoma · Metastatic Lung Non-Squamous Non-Small Cell Carcinoma · Recurrent Lung Non-Squamous Non-Small Cell Carcinoma · Stage IIIB Lung Cancer AJCC v8
United States
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung CancerRecruiting
NCT06712355Phase 3Updated Jul 24, 2026
Sponsor: BioNTech SE
Extensive-stage Small-cell Lung Cancer
United States, Australia, China, France, Germany +9 more
ACP-204 in Adults With Alzheimer's Disease PsychosisRecruiting
NCT06159673Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: ACADIA Pharmaceuticals Inc.
Alzheimer's Disease Psychosis
United States, Brazil, Bulgaria, Chile, Czechia +7 more
Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use DisorderRecruiting
NCT07644052Phase 3Updated Jul 24, 2026
Sponsor: PleoPharma, Inc.
Cannabis Withdrawal
United States
Comparison of Alpha Blockers (Terazosin and Tamsulosin) in Reducing Ureteral Stent Related SymptomsRecruiting
NCT06966804Phase 3Updated Jul 24, 2026
Sponsor: Penang Hospital, Malaysia
Stent Related Symptoms
Malaysia
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate CancerRecruiting
NCT07213674Phase 3Updated Jul 24, 2026
Sponsor: Amgen
Metastatic Castration-resistant Prostate Cancer
United States, Australia, Austria, Belgium, Canada +13 more
Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum ThrombosisRecruiting
NCT07140211Phase 3Updated Jul 24, 2026
Sponsor: Marc Blondon
Venous Thromboembolism (VTE) · Postpartum
Switzerland
Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruiting
NCT06441006Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: University of California, San Francisco
Tuberculosis, Pulmonary · Tuberculosis, Multidrug-Resistant · Tuberculosis, MDR
Mongolia, Pakistan, Peru, Uganda, Vietnam
TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With PolyneuropathyRecruiting
NCT07223203Phase 3Updated Jul 23, 2026
Sponsor: Alnylam Pharmaceuticals
Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy · hATTR-PN
United States, Australia, Brazil, Cyprus, France +11 more
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe AsthmaRecruiting
NCT06023589Phase 3Updated Jul 23, 2026
Sponsor: AstraZeneca
Asthma
United States, Argentina, Brazil, Canada, China +17 more
Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast CancerRecruiting
NCT06606730Phase 3Updated Jul 23, 2026
Sponsor: UNICANCER
Breast Cancers · Triple Negative Breast Cancer (TNBC)
Belgium, France
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)Recruiting
NCT07060807Phase 3Updated Jul 23, 2026
Sponsor: Merck Sharp & Dohme LLC
Breast Neoplasms
United States, Argentina, Australia, Brazil, Canada +21 more
An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's DiseaseRecruiting
NCT07724132Phase 3Updated Jul 23, 2026
Sponsor: University College, London
Alzheimer's Disease (AD) · Mild Cognitive Impairment Due to Alzheimer's Disease · Alzheimer Disease Dementia
United Kingdom
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric PatientsRecruiting
NCT06372964Phase 3Updated Jul 23, 2026
Sponsor: Intra-Cellular Therapies, Inc.
Bipolar Depression
United States, Colombia, India, Serbia
PSMA PET Combined With MRI for the Detection of PCaRecruiting
NCT07052214Phase 3Updated Jul 23, 2026
Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited
PCA · Prostate Cancer · Prostatic Neoplasm · PSMA PET
United States, Australia
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic DiseaseRecruiting
NCT07332481Phase 3Updated Jul 23, 2026
Sponsor: EMD Serono Research & Development Institute, Inc.
Systemic Lupus Erythematosus (SLE) · Cutaneous Lupus Erythematosus (CLE)
United States, Japan
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruiting
NCT05675410Phase 3Updated Jul 23, 2026
Sponsor: National Cancer Institute (NCI)
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
United States, Canada, Puerto Rico
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental VitiligoRecruiting
NCT06548360Phase 3Updated Jul 23, 2026
Sponsor: Incyte Corporation
NonSegmental Vitiligo
United States, Canada
Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BALRecruiting
NCT06134492Phase 3Updated Jul 23, 2026
Sponsor: Jena University Hospital
Pneumonia, Viral · Ventilator Associated Pneumonia · Community-acquired Pneumonia · Herpes Simplex
Germany
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP TrialRecruiting
NCT05863195Phase 3Updated Jul 23, 2026
Sponsor: ECOG-ACRIN Cancer Research Group
Metastatic Colorectal Carcinoma · Metastatic Malignant Neoplasm in the Liver · Stage IV Colorectal Cancer AJCC v8 · Unresectable Colorectal Carcinoma
United States
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)Recruiting
NCT06246916Phase 3Updated Jul 23, 2026
Sponsor: Regeneron Pharmaceuticals
Melanoma
United States, Canada
A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric CancerRecruiting
NCT07673887Phase 3Updated Jul 23, 2026
Sponsor: Astellas Pharma Global Development, Inc.
Gastric Adenocarcinoma · Gastroesophageal Junction (GEJ) Adenocarcinoma
Puerto Rico

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