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A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07)Recruiting
NCT07502300Phase 3Updated Jul 27, 2026
Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.
Extensive-stage Small-cell Lung Cancer
China
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)Recruiting
NCT05125302Phase 3Updated Jul 27, 2026
Sponsor: AbbVie
Migraine
United States, Puerto Rico
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic AdenocarcinomaRecruiting
NCT07562152Phase 3Updated Jul 27, 2026
Sponsor: Immuneering Corporation
Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC · PDAC - Pancreatic Ductal Adenocarcinoma
United States, Australia
Phase 3 Study of LUM-201 in Children With Growth Hormone DeficiencyRecruiting
NCT06948214Phase 3Updated Jul 27, 2026
Sponsor: Lumos Pharma
Growth Hormone Deficiency (GHD)
United States, Australia, Chile, New Zealand, Thailand +1 more
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)Recruiting
NCT06952504Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Endometrial Cancer
United States, Argentina, Australia, Austria, Belgium +29 more
Phase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid TumorsRecruiting
NCT06658353Phase 3Updated Jul 27, 2026
Sponsor: Jiangsu vcare pharmaceutical technology co., LTD
Locally Advanced Solid Tumor
China
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian CancerRecruiting
NCT06072781Phase 3Updated Jul 27, 2026
Sponsor: Verastem, Inc.
Low Grade Serous Ovarian Cancer
United States, Australia, Belgium, Canada, Denmark +11 more
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)Recruiting
NCT06312176Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Breast Neoplasms
United States, Argentina, Australia, Belgium, Brazil +35 more
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])Recruiting
NCT04267848Phase 3Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Lung Non-Small Cell Carcinoma · Lung Non-Small Cell Squamous Carcinoma · Lung Non-Squamous Non-Small Cell Carcinoma · Stage II Lung Cancer AJCC v8
United States, Guam
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast CancerRecruiting
NCT05894239Phase 3Updated Jul 27, 2026
Sponsor: Hoffmann-La Roche
Metastatic Breast Cancer
United States, Argentina, Australia, Belgium, Brazil +24 more
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or CarcinosarcomaRecruiting
NCT05256225Phase 3Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Endometrial Carcinoma · Endometrial Clear Cell Adenocarcinoma · Endometrial Dedifferentiated Carcinoma · Endometrial Endometrioid Adenocarcinoma
United States, Puerto Rico, South Korea
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASHRecruiting
NCT07221188Phase 3Updated Jul 27, 2026
Sponsor: GlaxoSmithKline
Non-alcoholic Fatty Liver Disease
United States, Hong Kong
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)Recruiting
NCT07570173Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
B-cell Acute Lymphoblastic Leukemia
Denmark, Israel, Italy, Japan, Netherlands +1 more
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and FibrosisRecruiting
NCT06215716Phase 3Updated Jul 27, 2026
Sponsor: Akero Therapeutics, Inc
NASH With Fibrosis · MASH With Fibrosis
United States, Argentina, Australia, Canada, France +13 more
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationRecruiting
NCT06647498Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: Washington University School of Medicine
Alzheimers Disease · Dementia · Alzheimers Disease, Familial
United States, Argentina, Australia, Canada, Colombia +10 more
Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)Recruiting
NCT06095583Phase 3Updated Jul 27, 2026
Sponsor: Shanghai Junshi Bioscience Co., Ltd.
Limited-stage Small Cell Lung Cancer (LS-SCLC)
China, Georgia, Netherlands, Spain, Taiwan +1 more
Phase III Clinical Study of VC005 Tablets in Adult Patients With Moderate to Severe Atopic DermatitisRecruiting
NCT06723080Phase 3Updated Jul 27, 2026
Sponsor: Jiangsu vcare pharmaceutical technology co., LTD
Moderate to Severe Atopic Dermatitis
China
Platform Trial For Cryptococcal Meningitis (PLATFORM-CM)Recruiting
NCT06666322Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: David Boulware
Hiv · Cryptococcal Meningitis
Uganda
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic CancerRecruiting
NCT07409272Phase 3Updated Jul 27, 2026
Sponsor: Astellas Pharma Global Development, Inc.
Pancreatic Cancer · Metastatic Pancreatic Cancer · Metastatic Pancreatic Adenocarcinoma
United States, Japan
A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)Recruiting
NCT07634471Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Follicular Lymphoma
United States, Israel, Spain, Taiwan, Turkey (Türkiye)
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)Recruiting
NCT07107945Phase 3Updated Jul 27, 2026
Sponsor: Boehringer Ingelheim
Chronic Kidney Disease
United States, Argentina, Australia, Belgium, Canada +13 more
A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With SeizuresRecruiting
NCT04715646Phase 3Updated Jul 27, 2026
Sponsor: UCB Biopharma SRL
Epilepsy
United States, Belgium, Czechia, France, Germany +6 more
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)Recruiting
NCT07318558Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Ovarian Neoplasms · Ovarian Cancer
United States, Argentina, Australia, Austria, Belgium +23 more
Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical RipeningRecruiting
NCT04949633Phase 3Updated Jul 27, 2026
Sponsor: University Hospital, Tours
Cervical Ripening · Unfavorable Cervix
France
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)Recruiting
NCT07489495Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Carcinoma, Renal Cell
United States, Argentina, Australia, Brazil, Czechia +12 more

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