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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular DiseaseRecruiting
NCT07064473Phase 3Updated Jul 27, 2026
Sponsor: Boehringer Ingelheim
Diabetes Mellitus, Type 2 · Hypertension · Cardiovascular Diseases
United States, Argentina, Australia, Austria, Belgium +46 more
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)Recruiting
NCT06841354Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Triple Negative Breast Neoplasms
United States, Argentina, Australia, Belgium, Brazil +29 more
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRTRecruiting
NCT05399537Phase 3Updated Jul 27, 2026
Sponsor: Vantive Health LLC
Regional Citrate Anticoagulation (RCA) · Continuous Renal Replacement Therapy (CRRT) · Acute Kidney Injury (AKI)
United States
Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruiting
NCT07613099Phase 3Updated Jul 27, 2026
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Allogeneic Stem Cell Transplantation · Lung Allograft Transplantation · Interstitial Lung Disease · Acute Lung Injury
United States
DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 InfectionRecruiting
NCT06203132Phase 3Updated Jul 27, 2026
Sponsor: ANRS, Emerging Infectious Diseases
HIV-1-infection
Brazil, Cameroon, Côte d’Ivoire, France, Mozambique +1 more
Study of Yupingfeng Powder Treating Allergic Rhinitis (AR)Recruiting
NCT06608017Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: Chinese University of Hong Kong
Allergic Rhinitis
Hong Kong
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)Recruiting
NCT07227402Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Renal Cell Carcinoma
United States, Argentina, Australia, Austria, Belgium +17 more
Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute SchizophreniaRecruiting
NCT07363577Phase 3Updated Jul 27, 2026
Sponsor: LB Pharmaceuticals Inc.
Schizophrenia
United States
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderRecruiting
NCT06951698Phase 3Updated Jul 27, 2026
Sponsor: Bristol-Myers Squibb
Bipolar-I Disorder With Mania or Mania With Mixed Features
United States, Argentina, Australia, Bulgaria, Hungary +4 more
Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint InRecruiting
NCT06745908Phase 3Updated Jul 27, 2026
Sponsor: ImmunityBio, Inc.
NSCLC Stage IV
United States, Canada, United Kingdom
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AMLRecruiting
NCT07007312Phase 3Updated Jul 27, 2026
Sponsor: Kura Oncology, Inc.
Acute Myeloid Leukemia (AML)
United States, Australia, Belgium, Canada, Czechia +11 more
A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With SchizophreniaRecruiting
NCT06882785Phase 3Updated Jul 27, 2026
Sponsor: Bristol-Myers Squibb
Schizophrenia
Japan
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)Recruiting
NCT06393374Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Triple-Negative Breast Cancer
United States, Argentina, Australia, Austria, Belgium +26 more
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)Recruiting
NCT07216703Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Cervical Cancer
United States, Argentina, Austria, Belgium, Brazil +22 more
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)Recruiting
NCT07419295Phase 3Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Bladder Cancer
United States, Argentina, Australia, Belgium, Brazil +11 more
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract CancerRecruiting
NCT04628767Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: National Cancer Institute (NCI)
Renal Pelvis and Ureter Urothelial Carcinoma
United States
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple MyelomaRecruiting
NCT06158841Phase 3Updated Jul 27, 2026
Sponsor: AbbVie
Multiple Myeloma
United States, Australia, Austria, Belgium, Canada +20 more
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal CancerRecruiting
NCT07525206Phase 3Updated Jul 27, 2026
Sponsor: AbbVie
Colorectal Cancer
United States, Belgium, Japan, Portugal, South Korea +2 more
52-week Open Label Safety-Tolerability StudyRecruiting
NCT07369154Phase 3Updated Jul 27, 2026
Sponsor: LB Pharmaceuticals Inc.
Schizophrenia
United States
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic ArthritisRecruiting
NCT04804553Phase 3Updated Jul 24, 2026
Sponsor: Amgen
Active Juvenile Psoriatic Arthritis
Austria, Belgium, France, Germany, Greece +10 more
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc DiseaseRecruiting
NCT07254806Phase 3Updated Jul 24, 2026
Sponsor: DiscGenics, Inc.
Degenerative Disc Disease
United States
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE TrialRecruiting
NCT06096844Phase 3Updated Jul 24, 2026
Sponsor: National Cancer Institute (NCI)
Advanced Lung Non-Small Cell Carcinoma · Stage IIIB Lung Cancer AJCC v8 · Stage IIIC Lung Cancer AJCC v8 · Stage IV Lung Cancer AJCC v8
United States
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)Recruiting
NCT07366034Phase 3Updated Jul 24, 2026
Sponsor: Boehringer Ingelheim
Fibrosing Interstitial Lung Disease
United States, Argentina, Australia, Belgium, Brazil +17 more
Different Medications to Induce LaborRecruiting
NCT06259097Phase 3Updated Jul 24, 2026
Sponsor: Icahn School of Medicine at Mount Sinai
Pregnancy · Labor
United States
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)Recruiting
NCT07440225Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: EyeBiotech Ltd.
Macular Degeneration · Age-Related Macular Degeneration · Choroidal Neovascularization · Wet Macular Degeneration
United States, Argentina, Australia, Israel, Latvia +3 more

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