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Orexin s Role in the Neurobiology of Substance Use DisorderRecruiting
NCT05630781NAUpdated Jul 27, 2026
Sponsor: National Institute on Drug Abuse (NIDA)
Nicotine Dependence
United States
Environment and Alcohol: A Pilot StudyRecruiting
NCT06860607Phase 1Updated Jul 27, 2026
Sponsor: National Institute on Drug Abuse (NIDA)
Alcohol Use Disorder
United States
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist TherapyRecruiting
NCT07728669NAUpdated Jul 27, 2026
Sponsor: Kazakh Academy of Nutrition
Type 2 Diabetes Mellitus (T2DM) · Obesity (Disorder) · Overweight · Metabolic Syndrome
Kazakhstan
ROADMAP Clinical TrialRecruiting
NCT06771050Phase 4Updated Jul 27, 2026
Sponsor: University of Newcastle, Australia
Prosthetic Joint Infections of Hip · Prosthetic Joint Infections of Knee · Large Joint Prosthetic Joint Infections
Australia, New Zealand
Salivary Cortisol and Hypercortisolism in Type 2 DiabetesRecruiting
NCT07156370N/AUpdated Jul 27, 2026
Sponsor: Shanghai 6th People's Hospital
Hypercortisolism · Type 2 Diabetes (T2DM)
China
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia GravisRecruiting
NCT04951622Phase 3Updated Jul 27, 2026
Sponsor: Janssen Research & Development, LLC
Myasthenia Gravis
United States, Australia, Belgium, Canada, China +12 more
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)Recruiting
NCT07519772Phase 1, Phase 2Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Lymphoma, Non-Hodgkin · Lymphoma, Follicular · Lymphoma, Large B-Cell, Diffuse
United States, Argentina, China, Israel, Italy +4 more
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationRecruiting
NCT05552157Phase 2, Phase 3Updated Jul 27, 2026
Sponsor: Washington University School of Medicine
Alzheimers Disease · Dementia · Alzheimers Disease, Familial
United States, Argentina, Australia, Canada, Colombia +10 more
Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.Recruiting
NCT07426796NAUpdated Jul 27, 2026
Sponsor: Medipol University
Postoperative Pain · Cryptorchidism
Turkey (Türkiye)
A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell LymphomaRecruiting
NCT04045470NAUpdated Jul 27, 2026
Sponsor: Dana-Farber Cancer Institute
Cutaneous T Cell Lymphoma · Peripheral T Cell Lymphoma
United States
Optimization of Antiretroviral Therapy in Patients With AIDS-Related LymphomaRecruiting
NCT07727642NAUpdated Jul 27, 2026
Sponsor: Shanghai Public Health Clinical Center
AIDS-related Lymphoma · HIV Infection
China
A Study to Learn More About the Safety of a Single Dose of BIIB144 and How it is Processed in the Body of Healthy Adult Participants Ages 18 to 55 Years Old as Compared to a PlaceboRecruiting
NCT07662148Phase 1Updated Jul 27, 2026
Sponsor: Biogen
Healthy Volunteer
United States
A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With ObesityRecruiting
NCT07728383Phase 4Updated Jul 27, 2026
Sponsor: Gila Therapeutics, Inc.
Obesity & Overweight
United States
Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular DiseaseRecruiting
NCT07717723NAUpdated Jul 27, 2026
Sponsor: University of California, Davis
Caregiver Burden · Stress · Depression · Anxiety
United States
Pharmacogenetics of Response to GLP1R AgonistsRecruiting
NCT05071898Phase 1Updated Jul 27, 2026
Sponsor: University of Maryland, Baltimore
Obesity · Diabetes Type 2
United States
Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialRecruiting
NCT06274749NAUpdated Jul 27, 2026
Sponsor: National Institute on Aging (NIA)
Healthy Volunteer
United States
A Study of Orelabrutinib in Patients With Primary Progressive Multiple SclerosisRecruiting
NCT07067463Phase 3Updated Jul 27, 2026
Sponsor: Zenas BioPharma (USA), LLC
Multiple Sclerosis (MS) Primary Progressive
United States, Bulgaria, Croatia, Czechia, Estonia +5 more
Study of Proteus Syndrome and Related Congenital DisordersRecruiting
NCT00001403N/AUpdated Jul 27, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Proteus Syndrome · PIK3CA Related Overgrowth Spectrum
United States
Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial FibrillationRecruiting
NCT07575269NAUpdated Jul 27, 2026
Sponsor: Boston Scientific Corporation
Paroxysmal Atrial Fibrillation (PAF) · Persistent Atrial Fibrillation
United States, Ireland
The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue MorbidityRecruiting
NCT06494878Phase 3Updated Jul 27, 2026
Sponsor: University of Calgary
Venous Thromboembolism · Postpartum Period · Aspirin · Low Molecular Weight Heparin
Belgium, Canada, Denmark, France, Ireland +2 more
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)Recruiting
NCT06818643Phase 1, Phase 2Updated Jul 27, 2026
Sponsor: Merck Sharp & Dohme LLC
Advanced Solid Tumors · Malignant Neoplasm
United States, Chile, China, France, Israel +7 more
VE303 for Prevention of Recurrent Clostridioides Difficile InfectionRecruiting
NCT06237452Phase 3Updated Jul 27, 2026
Sponsor: Vedanta Biosciences, Inc.
Clostridium Difficile · Clostridium Difficile Infections · Clostridium Difficile Infection Recurrence · Clostridioides Difficile Infection
United States, Australia, Belgium, Brazil, Bulgaria +19 more
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast CancerRecruiting
NCT06369285Phase 2Updated Jul 27, 2026
Sponsor: Puma Biotechnology, Inc.
Hormone Receptor Positive HER-2 Negative Breast Cancer · Metastatic Breast Cancer · Recurrent Breast Cancer
United States, Portugal, Spain
The CARDIOPROTECT TrialRecruiting
NCT07654426Phase 2Updated Jul 27, 2026
Sponsor: Beth Israel Deaconess Medical Center
Diffuse Large B-cell Lymphoma (DLBCL) · Cardiotoxicity · Lymphoma
United States
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System AtrophyRecruiting
NCT07197866Phase 2Updated Jul 27, 2026
Sponsor: Teva Branded Pharmaceutical Products R&D LLC
Multiple System Atrophy
United States, France, Germany, Israel, Italy +2 more

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